Clinical & Prescribing Information
1. Therapeutic Indications & Overview
Dydrofact 10 contains Dydrogesterone, a synthetic progestogen that is highly selective for progesterone receptors. Unlike some other synthetic options, dydrogesterone does not cause androgenic side effects, making it highly suitable for sensitive female health requirements.
Female Infertility, Menstrual Problems, Premenstrual Syndrome, Endometriosis
2. Mechanism of Action
Dydrogesterone acts directly on the uterus, producing a complete secretory endometrium in estrogen-primed women. It provides crucial hormonal support in the luteal phase without suppressing ovulation, facilitating healthy endometrial development and embryo implantation.
3. Dosage & Administration
Generally prescribed at 10mg once or twice daily depending on the specific indication (e.g., threatened miscarriage, habitual abortion, or endometriosis). Always follow a registered gynaecologist's advice.
*Note: The exact dosage schedule must be tailored to the individual clinical response and patient profile under doctor supervision.
4. Clinical Efficacy & Safety Profile
Clinical research indicates that Dydrogesterone has excellent oral bioavailability and is highly effective in reducing the risk of miscarriage in women with threatened or recurrent pregnancy loss. Its longer half-life of 18 hours ensures stable systemic levels.
5. Precautions & Contraindications
Before starting Dydrogesterone therapy, perform a thorough medical assessment. It should be used with caution in patients with hepatic impairment, a history of thromboembolic disorders, or undiagnosed abnormal vaginal bleeding.